產(chǎn)品屬性：
產(chǎn)品名稱 | RIPK1-IN-4 |
規(guī)格 | 1mg、5mg、10mg、25mg、50mg、100mg、200mg、500mg |
貨號 | EY-01Y12291 |
Cas No.: 1481641-08-0
別名: N/A
化學名: N/A
分子式: C23H23N5O2
分子量: 401.46
溶解度: DMSO: 250 mg/mL (622.73 mM)
儲存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase[1].[1]. Harris PA, et al. Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis. ACS Med Chem Lett. 2013 Nov 4;4(12):1238-43.
特別提醒公司產(chǎn)品僅供科研使用
