產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | XY028-133 |
規(guī)格 | 10mM*1 mL in DMSO、5 mg、10 mg、25 mg、50 mg、100 mg |
貨號(hào) | EY-01Y13149 |
Cas No.: 2229974-73-4
別名: N/A
化學(xué)名: N/A
分子式: C53H67N11O7S
分子量: 1002.23
溶解度: DMSO : 50 mg/mL (49.89 mM; Need ultrasonic)
儲(chǔ)存條件: Store at -20°C, sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity[1].XY028-133 (1 and 3 μM, 24 h) significantly decreases CDK4/6, Cyclin A, PLK1 and pRb protein levels in A375 cells[1].[1]. JIN, Jian， et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027.
特別提醒公司產(chǎn)品僅供科研使用
