產(chǎn)品屬性：
產(chǎn)品名稱(chēng) | Salvinorin B Mesylate |
規(guī)格 | 500μg、1mg、5mg |
貨號(hào) | EY-01Y16053 |
Cas No.: 862073-79-8
別名: N/A
化學(xué)名: N/A
分子式: C22H28O9S
分子量: 468.5
溶解度: DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:7): 0.125 mg/ml,Ethanol: slightly soluble
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Salvinorin B mesylate (Mesyl Sal B) is a selective κ-opioid receptor agonist that is more potent than salvinorin A in CHO cells transfected with the human κ-opioid receptor (EC50s = 30 and 40 nM, respectively). It is a mesylated version of salvinorin B and is highly selective for κ-opioid receptors over μ- and δ-opioid receptors. In vitro, it increases dopamine uptake via the dopamine transporter (DAT) in an ERK1/2-dependent manner but does not alter expression of DAT on the cell membrane. In rats, it increases the pain threshold and blocks reinstatement of cocaine drug-seeking.
特別提醒公司產(chǎn)品僅供科研使用
