產(chǎn)品屬性：
產(chǎn)品名稱 | SI-2 |
規(guī)格 | 1mg、5mg、10mg、25mg |
貨號(hào) | EY-01Y16920 |
Cas No.: 380537-35-9
別名: N/A
化學(xué)名: (1E)-1-(2-pyridinyl)-ethanone-2-(1-methyl-1H-benzimidazol-2-yl)hydrazone
分子式: C15H15N5
分子量: 265.3
溶解度: 20mg/mL in ethanol, 30mg/mL in DMSO or DMF
儲(chǔ)存條件: Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
SI-2 is an inhibitor of steroid receptor coactivator 3 (SRC-3). It has been shown to selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells through direct physical interactions with SRC-3.1 SI-2 induces death in various breast cancer cells with IC50 values of 3-20 nM without affecting normal cell viability.[1] At 2 mg/kg, SI-2 can also inhibit primary tumor growth and reduce SRC-3 protein levels in an MDA-MB-468 breast cancer mouse model.[1]
特別提醒公司產(chǎn)品僅供科研使用
