產品屬性：
產品名稱 | Sarafloxacin-d8 (hydrochloride) |
規(guī)格 | 500 μg、1 mg、5 mg、10 mg |
貨號 | EY-01Y17931 |
Cas No.: N/A
別名: N/A
化學名: N/A
分子式: C20H9D8F2N3O3·HCl
分子量: 429.9
溶解度: DMSO: soluble
儲存條件: -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產品描述：
Sarafloxacin-d8 is intended for use as an internal standard for the quantification of sarafloxacin by GC- or LC-MS. Sarafloxacin is a fluoroquinolone antibiotic.1,2 It is active against various clinical isolates of bacteria, including Bacteroides, Fusobacterium, Eubacterium, Actinomyces, and Peptococcus (MICs = 0.5-2 μg/ml).1 Sarafloxacin inhibits P. aeruginosa DNA gyrase.3 It decreases air sac lesion severity in a chick model of E. coli-induced colisepticemia when administered at a dose of 8 mg/kg in the drinking water 24 hours per day for five days.2 Formulations containing sarafloxacin have previously been used in the treatment of bacterial infections in poultry.1.Bansal, M.B., and Thadepalli, H.Activity of difloxacin (A-56619) and A-56620 against clinical anaerobic bacteria in vitroAntimicrob. Agents Chemother.31(4)619-621(1987)
2.Charleston, B., Gate, J.J., Aitken, I.A., et al.Comparison of the efficacies of three fluoroquinolone antimicrobial agents, given as continuous or pulsed-water medication, against Escherichia coli infection in chickensAntimicrob. Agents Chemother.42(1)83-87(1998)
3.Moir, D.T., Di, M., Opperman, T., et al.A high-throughput, homogeneous, bioluminescent assay for Pseudomonas aeruginosa gyrase inhibitors and other DNA-damaging agentsJ. Biomol. Screen.12(6)855-864(2007)
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