產(chǎn)品屬性：
產(chǎn)品名稱 | 2-Aminopurine |
規(guī)格 | 100 mg |
貨號 | EY-01Y21219 |
Cas No.: 452-06-2
別名: N/A
化學(xué)名: N/A
分子式: C5H5N5
分子量: 135.13
溶解度: DMSO : 5 mg/mL (37.00 mM)|H2O : 1.35 mg/mL (9.99 mM)
儲存條件: Store at 2-8°C, protect from light
General tips:For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition:Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics[1][2].2-Aminopurine (2AP) is not valuable as afluorescent label because its fluorescence is highly quenched by stacking with the natural bases, when it is inserted in anoligonucleotide. However, it is this very susceptibility to interbase quenching that makes 2AP an exquisitely sensitivefluorescent probe of nucleic acid structure[1]. 2-Aminopurine differs from adenine (6-aminopurine) only in the position of the exocyclic amine group, and yet its fluorescence intensity is one thousand times that of adenine[1].
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